Thus, hormonal changes in pregnancy that influence immunological responses to viral pathogens, together with the physiological transition to a Th2 environment favoring the expression of anti-inflammatory cytokines (IL-4 and IL-10) and other unidentified immune adaptations, may serve as the predominant immune response to SARS-CoV-2, resulting in the lesser severity of COVID-19 [13,15]. This evidence concerns the gene IL10 and COVID-19.