KCNQ1 and chronic obstructive pulmonary disease: Moreover, dominant LQT1 mutations expressed in the heart and brain of mice, and corresponding to those linked with the genetic LQTS disorders Romano–Ward syndrome and Jervell and Lange-Nielsen syndrome in humans, resulted in both cardiac arrhythmias and epileptic seizures, revealing a potential dual neuro-cardiac arrhythmogenic role for KCNQ1 mutations [3].