The mRNA expression of RIPK1, RIPK3, and MLKL in tumor tissues was significantly correlated with each other (r = 0.46, P <0.001, between RIPK1 and RIPK3; r = 0.35, P <0.001, between RIPK1 and MLKL; r = 0.43, P <0.001, between RIPK3 and MLKL; Figure 2). Here, RIPK1 is linked to neoplasm.