Using immunohistochemistry, Wu et al. 16 addressed that ovarian cancer PDXs expressed some similar proteins to original cancer such as nervous tissue marker (Syn), epithelial tissue marker (CK7), interstitial tissue marker (Vimentin), tumor protein p53, proliferating cell nuclear antigen, proliferative marker antigen Ki-67, and nuclear factor erythroid 2 like 2 (Nrf2). Here, TP53 is linked to ovarian cancer.