Both in the univariate Cox regression analysis and after adjusted by age, gender, smoking status, histological type and stage, we found that SAPCD1 rs707937 was significantly associated with OS of lung cancer patients received platinum-based chemotherapy (Additive model: P=0.0003, OR=0.75, 95% CI =0.35-1.14; Dominant model: P=0.001, OR=0.97, 95% CI =0.38-1.56; recessive model: P=0.008, OR=0.98, 95% CI =0.26-1.70) (Table 4). Here, SAPCD1 is linked to lung cancer.