ACTL10 and acute myeloid leukemia: In addition, the OS in the ACTL10 RNA-high expression group and the ACTL10 RNA-low expression group in 78 patients with CN-AML from the GSE12417 dataset (validation cohort) was subsequently investigated; the result were consistent with the previous results, demonstrating that the OS of the ACTL10 RNA-high expression group was increased compared with the ACTL10 RNA-low expression group (OS, P<0.0001; log-rank test; Fig. S3).