FCGR3B and autoimmune disease: Similarly, a rat paralog of the Fcgr3 gene (Fcgr3-rs) was identified as causing glomerulonephritis, and the result was promptly translated to the human: low copy number of FCGR3B, an orthologue of rat Fcgr3, was associated with glomerulonephritis in the autoimmune disease systemic lupus erythematosus [471].