Insufficientstandardization of IgA aPL assays contributes to this enigma, heterogeneity wasevident when comparing different diagnostic kits.16, –18 In addition, the frequentco-occurrence of other isotypes with IgA makes it even more troublesome to ascertainthe individual role of IgA aPL in SLE. The gene discussed is CD79A; the disease is systemic lupus erythematosus.