It is consistently reported that IgA anti-β2GPI antibodies are the mostcommonly occurring aPL in SLE patients with African ancestry.2,4,19,29 In contrast to our current study methodology, all previous studies on aPL inSLE among African populations have either used common manufacturers’ cut-offs, mostprobably based on Caucasian controls, or have adjusted cut-offs based on parametricstatistics assuming normal distribution of aPL levels. The gene discussed is APOH; the disease is systemic lupus erythematosus.