previously showed that IgA anti-domain 4/5 and not IgA anti-D1 areassociated with SLE.40 In a recent study by Serrano et al., APS patients with thrombosis more oftenhad IgA antibodies against β2GPI domains 3, 4 and 5 than they had IgA anti-D1.41 These findings conformed to an earlier study by Blank et al., showing thatthree peptides interfering with binding of monoclonal antibodies against domains 1and 2, 3 and 4 prevented the development of experimental APS.42 In our study, neither IgA anti-β2GPI nor IgA anti-D1 associatedwith thrombotic or obstetric events among Sudanese patients. The gene discussed is APOH; the disease is systemic lupus erythematosus.