Therefore, the Cytosponge-TFF3 procedure had a positive predictive value of 59% (131 of 221 confirmatory endoscopies in patients with a positive Cytosponge-TFF3 result) for Barrett's oesophagus, dysplasia, or oesophago-gastric cancer (table 2, 3). Here, TFF3 is linked to Barrett esophagus.