We identified 140 Barrett's oesophagus diagnoses in the intervention group (127 in patients who underwent the Cytosponge-TFF3 procedure, and 13 in patients who did not undergo the Cytosponge-TFF3 procedure) compared with 13 diagnoses in the usual care group (table 2, 3; see appendix pp 131–32 for the corresponding tables for randomisation groups and a breakdown of the length of Barrett's oesophagus detected). This evidence concerns the gene TFF3 and Barrett esophagus.