UCN2 and colorectal carcinoma: Likewise, the co-upregulated genes in CRC experiments with a single-drug perturbation, were highly enriched in “SRP-dependent cotranslational protein targeting to membrane” (biological process), “cytosolic ribosome” (cellular component), and “ketosteroid monooxygenase activity” (molecular function) (Fig. 10 and Supplementary Table 10).