HLA-DRA and Epstein-Barr virus infection: For EBV infection, GWAS of 3289 individuals, replicated our previous finding11 rs9272371 in HLA-DQA1 (p = 5.24 × 10−33, β = −0.37) and identified a distinct secondary signal, rs3129867 in HLA-DRA (pcond = 6.01 × 10−11, β = −0.17) (Supplementary Table 3).