To investigate the inter-individual variation of IgG antibody responses marking different stages of the viral life cycles (latent vs lytic) to KSHV and EBV infections, distributions of antibody levels were determined to the latent (ORF73, K10.5, EBNA-1) and lytic antigens (K8.1, VCA and EAD) in 4365 individuals. Here, COLQ is linked to Epstein-Barr virus infection.