PANX1 is also linked to neurodevelopmental disorders indirectly through its interacting partner CRMP2 and its downstream signaling effectors and interactors, purinergic receptors (Boyce et al., 2015; Boyce and Swayne, 2017; for review, see Swayne and Boyce, 2017). The gene discussed is PANX1; the disease is neurodevelopmental disorder.