WT1 methylation was also significantly associated with the risk of luminal B subtype breast cancer with ORs of 2.49 (95% CI: 1.13–5.51, P = 0.02) and 3.23 (95% CI: 1.34–7.80, P = 0.01) after multivariable and PS adjustment. Here, WT1 is linked to breast cancer.