Repeat-associated RNA toxicity mechanisms are a key driver of pathology underlying DM1 (myotonic dystrophy, type 1; OMIM # 160900) and DM2 (myotonic dystrophy, type 2; OMIM # 602668) (Sznajder and Swanson, 2019), neurological diseases attributed to trinucleotide repeat expansions in non-coding regions of DMPK and CNBP respectively. The gene discussed is CNBP; the disease is myotonic dystrophy type 2.