CASP6 and infection: However, upon infection with Salmonella, both Gsdmd–/–;Bid–/–;Mlkl–/–;Casp3–/–;Casp7–/–;Casp9–/– and Gsdmd–/–;Bid–/–;Mlkl–/–;Casp3–/–;Casp6–/–;Casp7–/–;Casp9–/– iBMDMs underwent substantial cell death, although this was delayed compared to WT iBMDMs (Figure 6A).