STAT3 was found to be constitutively active, typically phosphorylation at Y705, in EBV-positive nasopharyngeal cell carcinoma [52–54], EBV-positive B cell lymphomas [55–57], and KSHV tumors [58], supporting the role of STAT3 activation in gammaherpesvirus-related cancers. The gene discussed is STAT3; the disease is cancer.