The mRNA expression of cytokines involved in neutrophil recruitment to cancer sites, such as colony‐stimulating factor‐2 (CSF‐2), CSF‐3 and chemokine (C‐X‐C motif) ligand 1 (CXCL1), was determined, and CSF‐2 and CSF‐3 were reduced and CXCL1 expression was increased in CT26‐mP2X7R cells (Figure 6B). The gene discussed is CXCL1; the disease is cancer.