In intracerebral hemorrhage, CD47 has the ability to accelerate the clearance of hematoma after intracerebral hemorrhage by activating M1-type macrophages and increasing their phagocytosis, significantly reducing brain swelling after hemorrhage, and improving brain tissue damage after acute and chronic intracerebral hemorrhage, which may also become a new target for the treatment of intracerebral hemorrhage [55]. This evidence concerns the gene CD47 and intracerebral hemorrhage.