Most increased regulators in tumor cases compared to normal cases were YTHDF2 (p < 0.001), FTO (p < 0.001), YTHDC1 (p < 0.001), YTHDC2 (p < 0.001), YTHDF1 (p < 0.001), KIAA1429 (p < 0.001), METTL3 (p < 0.010), WTAP (p < 0.001), RBM15 (p < 0.001), HNRNPC (p < 0.001), and ALKBH5 (p = 0.001). The gene discussed is METTL3; the disease is neoplasm.