IL6 and cancer: To get insights into the antitumoral effects induced by hazu-MSC-CM, namely, if these are due to a crosstalk between the induced azurin expression and the native secretome of MSC, we evaluated the expression of four cytokines expressed by MSC that have been described to have a role in MSC interaction with cancer cells: inteuleukin-6 (IL6) (Kidd et al., 2009), vascular endothelial growth factor (VEGF) (Vera et al., 2019), stromal derived factor 1 alpha (SDF1-α) (Liu et al., 2010), and transforming growth factor beta (TGF-β) (Markell et al., 2010).