IFNB1 and Ebola hemorrhagic fever: Broad antiviral spectrum; Efficacy against coronaviruses, both in vitro and in vivo studies; The safety profile has been demonstrated in Ebola studies; Superior efficacy of the Lopinavir/Ritonavir/IFNbeta combination in animal model studies. Adults and children weighing 40 kg or more: Loading dose of 200 mg by IV infusion on day 1, followed by 100 mg by IV infusion once daily on days 2–10 or followed by 100 mg by IV infusion once daily on days 2–5.