AR and posterior cortical atrophy: A recent study on ctDNA isolated from enriched CTC from surgically treated PCa patients undergoing androgen deprivation therapy showed a significant association between an androgen receptor transcriptional variant (V7-AR) detected by ddPCR, and a high probability of developing castration-resistant (CRPCa) and (mCRPCa) metastatic castration resistant PCa (33).