AFP and laryngotracheoesophageal cleft: This study is aimed at evaluating the serum levels of these eight lncRNAs among patients with HCC, chronic hepatitis B (CHB), and liver cirrhosis (LC) and healthy participants and at assessing the diagnostic values of these lncRNAs and their combination with AFP, thus to identify a panel of circulating lncRNAs as a tool for the diagnosis of HCC.