Several studies have already developed several multiple biomarker panels to increase diagnostic accuracy, such as the lncRNA panel established by lncRNA-LET, PVT1, PANDAR, PTENP1, and linc00963 for the diagnosis of clear cell renal cell carcinoma [13] and a panel consisting of two lncRNAs (SOX2OT and ANRIL) and three tumor markers (CEA, CYFRA21-1, and SCCA) for the detection of non-small-cell lung cancer [31]. The gene discussed is PVT1; the disease is clear cell renal carcinoma.