BRCA2 and breast carcinoma: A total of 242 (46.8%) had their genetic testing because they were 50 years of age or younger with one or more close relatives with breast cancer at any age; 40 (16.5%) of them were positive for BRCA1 or BRCA2. Among the 333 patients who were 40 years of age or younger, the pathogenic/likely pathogenic mutations were observed in 44 (13.2%) patients, Table 2.