Thus, in summary, in case of inflammatory pathway leading to cytokine storm, pro-inflammatory factors such as IL-6, IL-8, IL-1β, and GM-CSF and chemokines such as CCL2, CCL-5, IP-10, and CCL3, together with reactive oxygen species have been attributed to cause acute respiratory distress syndrome (ARDS) leading to pulmonary fibrosis and death. This evidence concerns the gene CCL2 and acute respiratory distress syndrome.