We then postulated that the PAg-treatment of tumor cell lines and/or their co-culture with Vγ9Vδ2 T cells could have an impact on RHOB activity using a fluorescent reporter based on the tripartite split-GFP system (22) which monitors the binding of activated RHOB to RBD, one of its effector domains (20). The gene discussed is RHOB; the disease is neoplasm.