IL12B and Chagas disease: For that matter we here performed a thorough genetic study focusing on 35 polymorphisms of IL4, IL12B, IL10, and IFNG using the Tag SNP approach, which represent all the genetic information contained in the mentioned genes, in a larger cohort (n = 433) of Brazilian Chagas disease patients, including CCC patients with or without ventricular dysfunction as well as asymptomatic patients.