Moreover, when we compared the percentages of FOXP3+Tbet+CD4+ Tregs vs. parasitemia, we saw no correlation in the control rat Ig (Figure 5F) or α-PD1 mAb (Figure 5G); however, LD01-treated mice showed a significant correlation with low percentages of Tregs being associated with lower parasitemia (Figure 5H). The gene discussed is CD4; the disease is parasitic infectious disease.