LAMP1 and neoplasm: Vaccination with HM SNAs generated a larger percentage of poly functional T cells, observed by comparing the number of double positive cytokine producing (IFN-γ+) and degranulating (CD107a+) CD8+ T cells, with HM SNA/PSA generating the highest number (p < 0.01, Figures 4D,F); these cells are critical for controlling tumor growth.