Furthermore, CD8+ T lymphocytes might be activated for virus peptide by macrophages, because tumors in mice caused by injected fibrosarcoma cells transfected with lymphocytic choriomeningitis virus [MCA102(gp33)] were infiltrated by CD8+ T lymphocytes, a few CD11c+ DCs and a high number of CD11b+ macrophages (44). Here, CD8A is linked to fibrosarcoma.