In our data, although there were high levels of pro-inflammatory cytokines in the re-stimulated splenocytes (IL-12p70 and IFN-γ) and single tumor cells (IFN-γ), the levels of anti-inflammatory cytokines (IL-10) in the re-stimulated splenocytes and single tumor cells were also increased. The gene discussed is IFNG; the disease is neoplasm.