Additionally, data from the GWAS catalog showed that MC4R rs17782313-T was associated with height in Europeans (26) and East Asians (27) and MC4R rs17782313-C was associated with increased BMI (in Europeans) (23, 28), obesity (in Europeans, both children and adults) (29), physical activity measurement, and BMI (in African Americans and Europeans) (30). This evidence concerns the gene MC4R and obesity due to melanocortin 4 receptor deficiency.