We have conducted four studies examining rats with graded levels of TH function (hypothyroidism to hyperthyroidism; Liu et al., 2008; Weltman et al., 2013), diabetic cardiomyopathy (Weltman et al., 2014), and hypertension (Weltman et al., 2015), with cardiac tissue T3 samples analyzed by Zucchi’s group. The gene discussed is TH; the disease is hypertensive disorder.