CACNA1D and cancer: The CaV1.3 is highly expressed in most types of cancer, including breast and prostate cancer, but also in brain, colorectal, gastric, bladder, lung, esophageal and uterine tumors (Chen et al., 2014; Wang et al., 2015a; Buchanan and McCloskey, 2016; Jacquemet et al., 2016).