The EBV latent transcripts EBER1 and LMP1 were not detected in any of the microdissected MS WM and GM samples (data not shown), a finding consistent with EBV infection being restricted to B cells accumulating in the MS brain connectival spaces (Serafini et al., 2007, 2010; Angelini et al., 2013; Veroni et al., 2018). This evidence concerns the gene PDLIM7 and Epstein-Barr virus infection.