TBK1 mutations were first linked to ALS (Cirulli et al., 2015; Freischmidt et al., 2015), FTD (Gijselinck et al., 2015; Le Ber et al., 2015) and ALS-FTD in 2015 (Pottier et al., 2015). The gene discussed is TBK1; the disease is frontotemporal dementia.