FUS and amyotrophic lateral sclerosis: Screening of FTD patients subsequently identified several FUS mutations in patients with bv-FTD either with or without concurrent ALS though the frequency of FUS mutations is much rarer in FTD than ALS cases (Ticozzi et al., 2009; Blair et al., 2010; Van Langenhove et al., 2010; Huey, Ferrari et al., 2012).