However, monocytes from patients with COPD incubated with 0.1 μg/mL LPS for 24 h produced less IL-8/CXCL8 and Gro-α/CXCL1 than monocytes from healthy donors did (Fig. 7b,c). The gene discussed is CXCL1; the disease is chronic obstructive pulmonary disease.