Other molecules, previously described as being associated with the response to helminth infection, were induced including trefoil factor 1 (TFF1) (25.9 fold)37, TFF2 (37.1 fold)38, regenerating islet-derived family, member 4 (REG4) (11.1 fold)39, the regulatory cytokine, amphiregulin (AREG) (2.2 fold)40, the goblet cell differentiation marker41,42 chloride channel accessory 1 (CLCA1, 3.5 fold) and mucin 2 (MUC2, 6.3 fold)43. The gene discussed is REG4; the disease is helminthiasis.