CD274 and neoplasm: The results showed that treatment with either anti-TNC or anti-PD-L1 antibodies only slightly improved T-cell-induced tumour killing, and a synergistic T-cell-induced tumour killing effect was observed when of anti-TNC and anti-PD-L1 antibodies were applied together in autophagy-impaired MDA-MB-231 cells (Fig. 8a).