CHCHD3 and type 2 diabetes mellitus: Fifteen proteins were identified as significantly altered, of which there was a reduced abundance of mitochondrial proteins, including cytochrome C oxidase VIC precursor (COX6C), coiled-coil-helix-coiled-coil-helix domain-containing protein 3 (CHCHD3), and ubiquinol-cytochrome C reductase complex ubiquinone-binding protein QP-C (UQCRQ), in obese and T2D individuals [99].