The combination of EpCAM with other tissue-specific markers such as, for instance, the asialoglycoprotein receptor 1 (ASGPR1), exclusively expressed in liver cells, allowed the separation of patients with liver disorders into patients with or without liver tumors (including hepatocellular or cholangiocellular carcinoma) [118]. This evidence concerns the gene ASGR1 and cholangiocarcinoma.