Similarly, in a glioblastoma model, genomic DNA (gDNA) sequences of tumor-associated genes were identified with a distinct distribution in either apoptotic bodies, MV or Exo isolated from human cancer stem cells, or from the blood of xenotransplanted mice, including specific detection of PIK3CA, EGFR, AKT1, and MDM2 sequences in MV [101]. This evidence concerns the gene PIK3CA and neoplasm.