EPCAM and cancer: Expanding the analyses on MV co-expressing EMMPRIN together with other tumor-associated molecules, such as epithelial cell adhesion molecule (EpCAM/CD326), MUC1/CA 15-3, or EGFR1, the numbers were not only significantly elevated in cancer patients versus controls but also associated with poor overall survival, thus suggesting that MV might indeed represent valuable prognostic cancer biomarkers.