In contrast, two studies found a statistically significant positive association between CRP and breast cancer risk for premenopausal women (CRP > 3 versus < 1 mg/L concentration and dichotomized at 10 mg/L concentration, respectively: HR 2.76, 95% CI: 1.18, 6.48 [36] and HR 1.18, 95% CI: 1.08, 1.30 [37]), but not for postmenopausal women (HR 1.34, 95% CI: 0.68, 2.64 [36] and HR 1.00, 95% CI: 0.93, 1.07 [37], respectively). The gene discussed is CRP; the disease is breast cancer.