IL6 and cancer: The antitumour properties of curcumin have been observed in cancers such as ovarian [111], breast [112], bladder [113], osteosarcoma [114], retinoblastoma [87] and oesophageal [115], which may be partly due to its ability to prevent inflammation by suppressing proinflammatory transcription factors, such as NF-κB [113,115], which leads to the downregulation of adipokines such as IL-6 [111] and leptin [109], and the upregulation of adiponectin, which affects lipid homeostasis [109,116].