KRAS and colorectal carcinoma: Our qPCR assay results demonstrate that while PRMT5 mRNA is 3.7-Fold (p < 0.05) overexpressed in KRAS WT CRC cells when compared to normal CCD 841 CoN colon cells, the KRAS mutant CRC cells show a more substantial 6.0-Fold (p < 0.005) overexpression of PRMT5 mRNA.