Most evidently, the Her2+ subtype was associated with copy number increases in the proto-oncogenes MLLT6, TBC1D3 and TAF15, but not in any tumor suppressor, while the luminal A subtype was associated with copy number increases in the proto-oncogenes GNAS, TRIM27, MDM2, MCF2 L and RARA, but in no tumor suppressor genes. This evidence concerns the gene TBC1D3 and neoplasm.