GRIA1 and obesity due to melanocortin 4 receptor deficiency: GluA1 surface expression was increased in obesity-prone but not obesity-resistant rats following 2 weeks of JF deprivation (Fig. 1b: two-way ANOVA group × diet interaction: F(1,36) = 16.1, p = 0.0003; main effect of group F(1,36) = 16.1, p = 0.0003; Sidak’s multiple comparisons, OP-CH vs. OP-JF, p < 0.0001).