SYNGAP1 and autism: Notably, SYNGAP1 is included in many intellectual disability/autism/epilepsy gene panels, which would likely have detected this variant, as coverage of exonic regions tends to be more complete on gene panels than on ES (Consugar et al., 2015; Xue, Ankala, Wilcox, & Hegde, 2015); and thus a gene panel may be better when a specific group of disorders are suspected.