AKT1 and myocardial infarction: The amount of activated (i.e., phosphorylated) 42/44-MAPK and Akt in MI P1 LAD ligation hearts at page P7 or P28 was significantly greater in MI hearts than in age matched normal (Fig 6); thus, MAPK, Wnt/β-catenin and Akt signaling were upregulated at protein level for at least 28 days after LAD ligation at P1.