Subgroup analysis revealed that the high expression of ABCC8 mRNA was correlated with good OS in astrocytoma (p = 0.000), low WHO grade (p = 0.022), high WHO grade (p = 0.000), IDH mutant (p = 0.000), IDH wildtype (p = 0.007), 1p/19q codel (p = 0.000), 1p/19q non codel glioma patients (p = 0.000) (Fig. 4). Here, ABCC8 is linked to central nervous system cancer.