Genes in these regions related to male fertility include ACAA1 (acetyl-CoA acyltransferase 1)51,52, PLCD1 (phospholipase C delta 1)53, EFCAB4B (CRACR2A; calcium release activated channel regulator 2A)54, GMCL1 (spermatogenesis associated germ cell-less protein expression decreased in male infertility)55, and MKRN2 (makorin ring finger protein 2)56. The gene discussed is CRACR2A; the disease is male infertility.